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Patches or gel: which HRT suits you

By The fira team Published 31 Aug 2026
The short answer

The short comparison

PatchGel
How oftenOnce or twice a weekEvery day
VisibleYes, a small adhesive squareNo
Drying timeNoneTwo to five minutes
Skin reactionsMore common, manageable by rotating sitesLess common
Dose adjustmentIn set patch strengthsFiner, by number of pumps
Transfer to othersNo riskReal risk until dry
Affected by heatAdhesion and absorption can be affectedLess so
Combined with progesterone in one productAvailable as a combined patchNo, progesterone taken separately

Why the route matters more than the choice

The important clinical decision is usually transdermal versus oral, not patch versus gel.

Oestrogen swallowed as a tablet is absorbed through the gut and passes through the liver, which affects clotting factors. Oestrogen through the skin does not. UK guidance recommends the transdermal route for women at increased risk of venous thromboembolism, including women with a BMI over 30.

So if you have been offered a patch or gel rather than tablets, that is likely a considered decision rather than an arbitrary one.

When a patch is the better fit

  • You would rather deal with it twice a week than every morning
  • You want the option of a combined patch containing both hormones
  • There are small children or a partner who would be in contact with an application site
  • Your mornings are busy enough without waiting for something to dry

When gel is the better fit

  • You have reacted to patch adhesive
  • You do not want anything visible on your skin
  • You want finer control over dose, adjusted a pump at a time
  • You live somewhere hot, or you swim daily, and patches have lifted

Progesterone, either way

If you have a womb, you need progesterone alongside oestrogen to protect the womb lining, whichever format you use. With gel that means a separate capsule. With patches you can have either a combined patch or a separate capsule.

If you have had a hysterectomy, oestrogen alone is usual.

What fira prescribes

We prescribe patches and capsules. We do not currently prescribe gel.

That is a formulary decision, not a clinical claim that gel is worse. If your assessment suggests gel is genuinely the better route for you, your clinician will tell you, and you should act on that rather than on what is convenient for us to supply.

Cost

On a fira plan the price is the same whichever format you are prescribed: one flat monthly price covering treatment, delivery and dose changes. Your dose can change; your price does not.

On an NHS prescription, formats are charged the same per item, and a prepayment certificate covers HRT items for a year.

How the decision actually gets made

A clinician weighs your clot risk, blood pressure, BMI, migraine history, skin, whether you still have a womb, whether you are still having periods, and what you will realistically keep doing. Then they propose a format and explain why.

That is what our free assessment collects.

Sources

Orbyt Group Ltd (company number 12623899). Fira is a brand of Orbyt Group Ltd, registered in England and Wales. This article is general information and is not personal medical advice. Always read the patient information leaflet supplied with your medicine.